Local AI Advisor

Can Mac Studio M1 Ultra 64 GB run Qwen3-Next 80B-A3B Instruct?

64 GB unified · 800 GB/s memory bandwidth · Qwen3-Next 80B-A3B Instruct has 81.3B parameters (3B active per token).

Short answer

Yes, excellent for chat and acceptable or better for every workload we test.

Best quantization for chat: 4-bit (43 GB of weights) on LM Studio. Generation: 150–210 tok/s, leaving about 9.9 GB free for your other apps.

How it rates for each workload

Same model and machine, different jobs. Agents and long documents send far bigger prompts than chat, so they need much more speed and memory.

WorkloadVerdictQuantGenerationFirst replyContext
Chatwith Open WebUIExcellent4-bit150–210 tok/sunder 1 s8KDetails
Coding questionswith ContinueExcellent4-bit150–200 tok/s≈2 s16KDetails
Coding in a repositorywith AiderAcceptable4-bit130–170 tok/s≈7 s32KDetails
Agentic codingwith OpenCodeAcceptable4-bit120–160 tok/s≈9 s32KDetails
Long documents (64K)with Open WebUIAcceptable4-bit90–120 tok/s≈25 s64KDetails

Speeds are estimates calibrated against measured benchmarks on similar hardware. “First reply” is the time to read the workload’s opening prompt. How we calculate

Get it running

Copy-paste commands for the 4-bit build with a 64K context. Ollama and llama.cpp download the file straight from Hugging Face.

ollama run hf.co/unsloth/Qwen3-Next-80B-A3B-Instruct-GGUF:Q4_K_M

Downloads 48.51 GB (Q4_K_M). Ollama's default context is small: set OLLAMA_CONTEXT_LENGTH=65536 before `ollama serve` for long prompts.

Different tool, context size or workload?

These pages use typical settings. The full check models your exact setup.