Can Ryzen AI Max+ 395 mini PC / Framework Desktop · 64 GB run MiniCPM5 2B?

64 GB unified · 256 GB/s memory bandwidth · MiniCPM5 2B has 2.5B parameters.

Short answer

Yes, excellent for chat and acceptable or better for every workload we test.

Best quantization for chat: Q8_0 (2.5 GB of weights) on Lemonade. Generation: 70–95 tok/s, leaving about 49 GB free for your other apps.

How it rates for each workload

Same model and machine, different jobs. Agents and long documents send far bigger prompts than chat, so they need much more speed and memory.

Workload	Verdict	Quant	Generation	First reply	Context
Chatwith Open WebUI	Excellent	Q8_0	70–95 tok/s	under 1 s	8K	Details
Coding questionswith Continue	Comfortable	Q8_0	65–90 tok/s	≈2 s	16K	Details
Coding in a repositorywith Aider	Acceptable	Q8_0	55–80 tok/s	≈8 s	32K	Details
Agentic codingwith OpenCode	Acceptable	Q8_0	55–75 tok/s	≈10 s	32K	Details
Long documents (64K)with Open WebUI	Comfortable	Q8_0	40–55 tok/s	≈40 s	64K	Details

Speeds are estimates calibrated against measured benchmarks on similar hardware. “First reply” is the time to read the workload’s opening prompt. How we calculate

Other models for Ryzen AI Max+ 395 mini PC / Framework Desktop · 64 GB

The best-rated models for chat on this machine.

Everything Ryzen AI Max+ 395 mini PC / Framework Desktop · 64 GB can run

Cheapest machines for MiniCPM5 2B

Hardware rated comfortable or better for chat, lowest price first.

Same chip, other memory: 128 GB

Different tool, context size or workload?

These pages use typical settings. The full check models your exact setup.

Open sourceCheck my exact setup