Can Desktop PC · RTX PRO 6000 Blackwell · 128 GB RAM run Llama 3.3 70B Instruct?

96 GB VRAM + 128 GB RAM · 1792 GB/s memory bandwidth · Llama 3.3 70B Instruct has 70.6B parameters.

Short answer

Yes, excellent for chat and acceptable or better for every workload we test.

Best quantization for chat: Q5_K_M (47 GB of weights) on Ollama. Generation: 17–25 tok/s, leaving about 43 GB free for your other apps.

How it rates for each workload

Same model and machine, different jobs. Agents and long documents send far bigger prompts than chat, so they need much more speed and memory.

Workload	Verdict	Quant	Generation	First reply	Context
Chatwith Open WebUI	Excellent	Q5_K_M	17–25 tok/s	under 1 s	8K	Details
Coding questionswith Continue	Comfortable	Q5_K_M	17–25 tok/s	≈4 s	16K	Details
Coding in a repositorywith Aider	Acceptable	Q6_K	14–19 tok/s	≈10 s	32K	Details
Agentic codingwith OpenCode	Acceptable	Q5_K_M	16–20 tok/s	≈15 s	32K	Details
Long documents (64K)with Open WebUI	Comfortable	Q5_K_M	13–18 tok/s	≈65 s	64K	Details

Speeds are estimates calibrated against measured benchmarks on similar hardware. “First reply” is the time to read the workload’s opening prompt. How we calculate

Get it running

Copy-paste commands for the Q5_K_M build with a 64K context. Ollama and llama.cpp download the file straight from Hugging Face.

ollama run hf.co/unsloth/Llama-3.3-70B-Instruct-GGUF:Q5_K_M

Downloads 49.95 GB (Q5_K_M). Ollama's default context is small: set OLLAMA_CONTEXT_LENGTH=65536 before `ollama serve` for long prompts.

Other models for Desktop PC · RTX PRO 6000 Blackwell · 128 GB RAM

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Different tool, context size or workload?

These pages use typical settings. The full check models your exact setup.

Open weights (restricted)Check my exact setup