Can Desktop PC · RTX PRO 6000 Blackwell · 128 GB RAM run gpt-oss-20b?
96 GB VRAM + 128 GB RAM · 1792 GB/s memory bandwidth · gpt-oss-20b has 20.9B parameters (3.6B active per token).
Short answer
Yes, excellent for chat and comfortable or better for every workload we test.
Best quantization for chat: MXFP4 (11 GB of weights) on Ollama. Generation: 310–420 tok/s, leaving about 83 GB free for your other apps.
How it rates for each workload
Same model and machine, different jobs. Agents and long documents send far bigger prompts than chat, so they need much more speed and memory.
| Workload | Verdict | Quant | Generation | First reply | Context | |
|---|---|---|---|---|---|---|
| Chatwith Open WebUI | Excellent | MXFP4 | 310–420 tok/s | under 1 s | 8K | Details |
| Coding questionswith Continue | Excellent | MXFP4 | 300–410 tok/s | under 1 s | 16K | Details |
| Coding in a repositorywith Aider | Comfortable | MXFP4 | 270–370 tok/s | ≈1 s | 32K | Details |
| Agentic codingwith OpenCode | Comfortable | MXFP4 | 260–350 tok/s | ≈2 s | 32K | Details |
| Long documents (64K)with Open WebUI | Excellent | MXFP4 | 200–270 tok/s | ≈5 s | 64K | Details |
Speeds are estimates calibrated against measured benchmarks on similar hardware. “First reply” is the time to read the workload’s opening prompt. How we calculate
Get it running
Copy-paste commands for the MXFP4 build with a 64K context. Ollama and llama.cpp download the file straight from Hugging Face.
ollama run hf.co/unsloth/gpt-oss-20b-GGUF:F16
Downloads 13.79 GB (F16). Ollama's default context is small: set OLLAMA_CONTEXT_LENGTH=65536 before `ollama serve` for long prompts.
Other models for Desktop PC · RTX PRO 6000 Blackwell · 128 GB RAM
The best-rated models for chat on this machine.
- Qwen3.6 35B-A3B260–360 tok/sExcellent
- Qwen3-Next 80B-A3B Instruct260–360 tok/sExcellent
- gpt-oss-120b≈180 tok/sExcellent
- Gemma 4 26B-A4B210–280 tok/sExcellent
- Qwen3.5 35B-A3B260–360 tok/sExcellent
- LFM2.5 24B-A2B530–720 tok/sExcellent
Cheapest machines for gpt-oss-20b
Hardware rated comfortable or better for chat, lowest price first.
- Mac mini M4 24 GB$999 · 25–35 tok/sExcellent
- Mac mini M6 24 GB$1,299 · 30–50 tok/sExcellent
- Laptop · Ryzen AI 9 HX 370 (Radeon 890M) · 32 GB$1,300 · 20–35 tok/sExcellent
- Laptop · Core Ultra 7 258V (Arc 140V) · 32 GB$1,300 · 18–30 tok/sExcellent
- Desktop PC · GeForce RTX 5060 Ti 16GB · 32 GB RAM$1,330 · ≈100 tok/sExcellent
- Desktop PC · GeForce RTX 4060 Ti 16GB · 32 GB RAM$1,350 · 50–85 tok/sExcellent
Different tool, context size or workload?
These pages use typical settings. The full check models your exact setup.